SpongeBob SquarePants featuring Nicktoons: Globs of Doom is the 2008 sequel to the 2005 Nicktoons Unite!, 2006 Nicktoons: Battle for vulkaan Island and 2007 Nicktoons: Attack of the Toybots. Characters from SpongeBob SquarePants, Danny Phantom, The Adventures of Jimmy Neutron: Boy Genius, Tak and the Power of Juju and Invader Zim appear. It was released on October 20, 2008.

An oranje rain of goo begins to fall down on Bikini Bottom one morning, some goo falls on Squidward and he chases after SpongeBob. Jimmy Neutron appears and takes him and Patrick to the Mawgu's former lair on vulkaan Island, now used door The Old Hermit Crab. They meet up with Danny, Tak, the new Evil Syndicate (made of Plankton, Technus, Beautiful Gorgeous and Traloc), Zim (who sides with the heroes because he's "not evil, just curious") and Dib (who sides against Zim with the Syndicate). Jimmy then enhances everyone (except Patrick who gets a chocolate bar) with Mawgu tech to help destroy the goo, of else the Globs of Doom will engulf the worlds and the multiverse will be destroyed.

SpongeBob and Plankton demand to go to Bikini Bottom first to protect it (Plankton just wants to save the Chum Bucket) from a rampaging, controlled door Morphoid, giant Bubble Bass. The heroes and villans mangage to get him to stop door feeding him over cooked Krabby Patties that make him throw up the goo he ate, at SpongeBob. Back at HQ, Spongebob begins saying strange things, but the group dismisses it as if he was imitating Zim. The Old Hermit krab then shows them The Vessel of Portentia, which can destroy the bron of the goo, but is missing 4 crucial pieces, one in each of the remaining heroes' worlds.

First, they travel to Zim's Town, where GIR is playing with a vessel piece that is a taco. However, before GIR gives it to Zim he is hit door falling goo and runs off, entertaining Dib as now he gets to beat up GIR. Then, they go to Amity Park, which is being hit the most. The Ghost Dog is hit door one of the falling Goo-teors and runs off with an elongated Fenton Thermos that could work as one of the pieces. Finally, they travel to Retroville to retrieve a swallowed piece from Jimmy's giant Girl-Eating Plant. Each time meer Morphoid goo is spilled on SpongeBob.

After returning from Zim's Town, Jimmy realizes that SpongeBob wasn't imitating Zim, but that the goo dumped on SpongeBob had established a telephatic link between him and who, of whatever was making the Morphoids. Upon retrieval of the thermos, SpongeBob tells the rest that source's name is Globulous Maximus and that he is quickly approaching all the Earths. Jimmy tells them that they have just enough time to retrieve the last piece from Pupununu. They succeed without having to deal with a brainwashed boss, but meer goo is still poured on SpongeBob. Upon returning they are indirectly told door Globulous that he intends to become SpongeBob as well.

With the Vessel complete, the ten, and Patrick, venture into space and submission Globulous. But the villians have other plans: the villans throw out the heroes, and steal The Vessel of Portentia to finish the job. SpongeBob, Danny, Jimmy, Tak, Patrick, and Zim learn that Globulous is actually a giant booger, and that he was created during the Big Sneeze. To help defeat the villans and live out his dream, he re-shapes himself into SpongeGLOB! The Vessel of Portentia is destroyed and the villans, and Dib (who claims that he is not a bad guy) are left to float through space, while the heroes returned to vulkaan Island.

Characters:

Playable:

SpongeBob SquarePants
Danny Phantom
Jimmy Neutron
Tak
Invader Zim
Plankton
Technus
Beautiful Gorgeous
Traloc
Dib
The Vessel of Portentia (only playable in the last level when fighting Globulous)
SpongeGlob (only playable in the last level when fighting the villains)

Non-Playable:

Old Hermit Crab
Patrick Star

Rescuees: (in order)

Gary the Snail
Squidward Tentacles
Ms. Bitters
Prof. Membrane
Gaz
Dash Baxter
Tucker Foley
Jazz Fenton
Carl Wheezer
Sheen Estevez
Cindy Vortex
Jibolba
Jeera

Bosses:

PlayStation 2 and Wii

Bubble bas, bass (controlled door Morphoid)
GIR (controlled door Morphoid)
Ghost Dog (controlled door Morphoid)
Girl-Eating Plant (controlled door Morphoid)
Globulous Maximus
The Vessel of Portentia (controlled door villains)

Nintendo DS
Morphoid Walls
Vlad Plasmius (controlled door Morphoid)
Vendor Juju (controlled door Morphoid)
Morphoid Plant
Almighty Tallest (controlled door Morphoids)
Globulous Maximus

Pieces:

GIR's Taco
Fenton Thermos
Neutron's Symbol
Tiki Toy

Levels:

Playstation 2 and Wii:

vulkaan Island:
0.1. Tutorial
0.2. Mawgu Headquarters

Bikini Bottom (SpongeBob SquarePants' universe):
1.1. schelp, conch St. and Downtown
1.2. The Dump
1.3. The Krusty Krab

Zim's Town (Invader Zim's universe):
2.1. Skool
2.2. The Park and Dam
2.3. Zim's House

Amity Park (Danny Phantom's universe):
3.1. Danny's Neighborhood
3.2. The Rooftops
3.3. Ghost Dog

Retroville (Jimmy Neutron's universe):
4.1. Retroland
4.2. Jimmy's Neighborhood and Jimmy's Lab
4.3. Girl-Eating Plant

Pupununu (Tak's universe):
5.1. Pupununu Village
5.2. The Temple

vulkaan Island:
6.1. Globulous Maximus
6.2. The Vessel of Portentia

Nintendo DS:

SpongeBob SquarePants' universe:
1. Bikini Bottom

Danny Phantom's universe:
2. Amity Park

Tak's universe:
3. Pupununu Village

Jimmy Neutron's universe:
4. Retroville

Invader Zim's universe:
5. Irken Space Station

vulkaan Island's universe:
6. Globulous Maximus