In resident evil 4,how do u kill the big chief?

u may want to tone down the difficulty, recently tried taking him on on hard mode: epic failure.

I don't know if this helps but I beat him in pro mode with the shotgun. Just kept firing!

just shot him with my sniper....10 times...haha

Buy a rocket launcher (if u have enough money) blast him with it and finish him off with the tmp.

i really dont even think its possible, when i fought him i had 4 first aid sprays most of my guns up to par and a couple of granades (more like 4 of 5) and when i was through with him i had nothing in my inventory i was completly empty.

u can use a hand granade of two when he's on the floor, then when he is unattached to his legs, he'll be hanging on the ceiling and structures, u can go up and start using the shotgun in his face several times.

u can also complete a RGY herb here, I think the red and the yellow are upstairs and the green down volgende to the entrance.

it totally easy i finished it 100000 times to kill him i kill him easly coz i have alunsher rocket lunsher in one hit he dies in no time colect money to buy lunsher and collect tresures as many how u can then buy rocket lunsher

u need to get a shotgun then look around and u will find shotgun ammo (10) then climb up the ladder get your handgun and right beside the shotgun ammo there will be a herb then climb the ladder where the herb was there will be a tank shot it.(there will be 3 herbs g r y )

Go in “Gun‘s blazing!” simple as that!

It depands on what weapon u have and how much ammo i beat the game a lot of times so now i have the chicago typewriter and the infinete lancher semi auto geweer-, geweer and trhe mine thrower with billions of dollars