I want watch a anime involved two diferents worlds of magical creatures.(if possible if cute characters)

InuYasha. that is perfect! and right now Rin-ne is only in manga but its great too!

(both door rumiko takahashi)

Well, right off the top, boven of my head...

Sands of Destruction, also known as World Destruction. It's not a very well known anime (like at all), but it fits your requirements, and it's the only one I can think of at the moment that does.

•I don't know if door "two different worlds" u mean metaphorically of literally, but I suppose it counts as both. meer so metaphorically though.
•Well, there are beastmen who walk and talk, if those count as magical creatures.
•The characters are pretty dang cute, in my opinion.

Watch these, you'll love them if u like magic anime! These have VERY cute characters!
Soul Eater
The Melancholy of Haruhi Suzumiya
FullMetal Alchemist(this one's sad though... It made me cry)
Ojamajo DoReMi
Pretear
Tokyo Mew Mew
Sailor Moon
Shugo Chara!
Hetalia(this one isn't really magic, unless u count England and the Flying Mint Bunny, but the characters are adorable and the anime is hilarious!)
Mermaid Melody Pichi Pichi Pitch
iDOLM@STER(watch it! It has nothing to with magic, but the characters are adorable, and it has the best muziek ever!!!)
CardCaptor Sakura
Tsubasa Reservoir Chronicles
Lucky Star(once again, no magic, but the characters are so cute and Konata is super funny!)
Ouran High School Host Club(again, no magic unless u count the Black Magic Club and Nekozawa-senpai, but it's so cute, the story is amazing, the characters a cute and funny, and the plot line is awesome)
Princess Tutu(this anime is definitely magical. Ballet, hart-, hart shards, evil authors coming back from the dead, psycho ravens controlling teenaged girls, how good can it get?)

Katekyo Hitman Reborn!
07 Ghost
Ao no Exorcist
:D

BLACK BUTLER! it has demons in it ^^

though i dont think they count as creatures... OH WELL!

I think u should watch "Shugo Chara" of "Pretty Cure" (all seasons maybe)
u will love them.

id say fairy tale is good! i luv it!
and gray is sexy!

shugo chara
lilpri
my melody and yes the one from hallo kitty
save me lollipop
salor moon
asarotte's toy

;) Fushigi Yuugi!

..and there's some others I know but
I actually forgot what they're called

Try tsubasa reservoir chronicles! It has loads of different worlds, And the characters are cute, right?

Fairy Tail!!

Dog Days has two Worlds and Magical Creatures: link