Even if Meredith is the "President for people with crappy lives" Izzie takes the cake. I wish they'd mention her sometime, or even better- she would come back once or so. Anyway, all three have had pretty crappy lives.

Followed by Alex and just then comes Meredith. Ironically, she isn't the only one who went through a lot. I think having cancer (Izzie) and being foster kid and in jail (Alex) trumps Mer's baggage.

alex had a drug adected father who bet his mother up,then his father leaft them,then he had to deal with his crazy mother and take care of his younger siblings,he was a foster kid,he went to jail. and that's only his child hood

as an adult,he had a girlfriend who went crazy on him,his wife almost died then leaft him for no reason,he was shot and almost died,his brother went crazy and almost killed their littel sister.

so is really a qeustion? he had the shitest life a person could have.

All three had it pretty bad, but deffinetly Alex, he had it the worst.

Izzie- two of her ex-lovers are dead, she hasn't seen her daughter in ages, left Alex, got cancer & heaps more.
Pretty bad, right?

She got cancer.Nuff said.